Applied Research
The Applied Research team is constructed of a staff from a range of disciplines (engineers, physicists, biologists) which generates a specialized multidisciplinary approach to biomedical engineering.
The team’s main initiative is the development of experimental and numerical methods for cardiovascular research applications with a specific aim to better understand the interactions between biological and mechanical systems. By effectuating current methods, the applied research team augments and improves research techniques used to generate future medical devices which are currently under development in the Cardiovascular Engineering (CVE) department.
- Numerische Simulation
Numerical Simulation
Numerical simulations and Computational Fluid Dynamics (CFD) techniques are implemented for the optimization of medical devices such as blood pumps, heart valves, dialyzers, and oxygenators. An innovative mass transfer model is under development to improve oxygenator designs by extrapolating key factors influencing device optimization. Additionally, the applied research team investigates current hemolysis and thrombogensis models used in the field of cardiovascular engineering and improves upon these to generate high standards for more accurate predictive calculations.
- PIV
Particle Image Velocimetry
Particle Image Velocimetry (PIV) is used as a validation tool for the numerical simulations. The flow field through medical devices and modeled anatomy can be visualized through transparent parts by tracking particles with high-speed cameras.
- Blood Lab
Blood Lab
Hemocompatibility and thrombogenicity laboratory testing of blood contacting CVE developed devices are also completed by the applied research team. Novel in vitro calcification tests are implemented on biological heart valve prostheses. Specialized testing facilities are utilized to investigate blood damage and hemolysis under defined flow conditions thereby permitting validation of self-developed mathematical blood damage models.
