Dr.rer.nat. Christiane Rosefort
Qualitätsmanagement & Regulatory Affairs
Projects:
HIA Room 1.01
+49 241 80 88616
rosefort(at)hia.rwth-aachen.de
Education
Studies
- Biology (Diploma) University of Marburg and TU Kaiserslautern
Main focus: Human biology, Genetics, Phytology
Subsidiary subject: Food chemistry / Environmental toxicology
Further Education
- Certified quality manager (ISO 9001; ZDH-Zert.)
- Certified project management associate (GPM, IPMA Level D)
Work
- (since 2010) Research assistant
Helmholtz-Institute, RWTH Aachen
Institute of Applied Medical Engineering (AME)
Dept. of Cardiovascular Engineering (CVE)
- (2010) Research assistant (PostDoc)
University Hospital, RWTH University; Aachen
Institute of pharmacology and toxicology
Dept. of molecular pharmacology - (2006-2009) Research assistant (Dissertation)
University Hospital, RWTH University; Aachen
Institute of pharmacology and toxicology
Dept. of molecular pharmacology
Publications
Dissertation
- Rosefort C: Elektrophysiologische Charakterisierung eines neuen heteromeren P2X-Rezeptors, einer P2X-Chimäre und neuer P2X-Rezeptor-Antagonisten. Aachen, 2010. - 147, XIII S. : graph. Darst. Aachen, Techn. Hochsch., Diss., 2010
Articles
- Bagi Y, Hausmann R, Rosefort C, Rettinger J, Schmalzing G, Müller CE: Discovery of Potent Competitive Antagonists and Positive Modulators of the P2X2 Receptor. J Med Chem. 2011 Jan 5.
- Wolf C, Rosefort C, Fallah G, Kassack MU, Hamacher A, Bodnar M, Wang H, Illes P, Kless A, Bahrenberg G, Schmalzing G, Hausmann R: Molecular determinants of potent P2X2 antagonism identified by functional analysis, mutagenesis, and homology docking. Mol Pharmacol. 2011 Apr;79(4):649-61. Epub 2010 Dec 29.
- Rosefort C, Fauth E, Zankl H: Micronuclei induced by aneugens and clastogens in mononucleate and binucleate cells using the cytokinesis block assay. Mutagenesis. 2004 Jul;19(4):277-84.
Posters
- Rosefort C, Duckwitz W, Hausmann R und Schmalzing G: Identification of P2X1 ectodomain residues important for channel assembly and function
Second Joint Italian-German Purine Club Meeting (Leipzig, 12.-15.09.2007) - El-Wahsch D, Fallah G, Eisele T, Rosefort C, Hausmann R und Schmalzing G: Role of disulfide bond formation on the assembly and cell surface expression of P2X1-receptors
Second Joint Italian-German Purine Club Meeting (Leipzig, 12.-15.09.2007) - Rosefort C, Fauth E und Zankl H: A fast assay to distinguish aneugens from clastogens by the cytokinesis-block micronucleus assay. Naunyn-Schmiedeberg´s Archives of Pharmacology, 367 (Suppl. 1), A637 (2003)
44. Frühjahrstagung der DPTG
