HomeDepartmentsTissueEngineering & BiomaterialsBioreactor Technologies

Bioreactor Technologies

Bioreactors are devices that attempt to mimic a physiological environment in order to achieve better cell and tissue growth and cell and tissue conditioning. Furthermore, bioreactors allow us to combine conventional technology with tissue engineering for the purpose of evaluating and testing the development of tissue engineered constructs.

Mechanical Conditioning

"Cells are lazy by nature"; it is therefore essential that cells used in the area of tissue engineering are exposed to some form of mechanical stimulation. For this reason we have developed bioreactor systems for a variety of specific applications (e.g. for cultivation of heart valves, vascular grafts, pericardium, cartilage).

Testing and Evaluating

Only by continuously testing our constructs and measuring their properties can we improve our techniques and design better systems that will allow us the production of more durable and more physiological tissue engineered constructs.

 

Figure 1: Heart valve conditioning system
Figure 2: Multi-purpose small construct bioreactor

Figure 3: Pulsatile flow bioreactor for vascular graft development
Figure 4: Heart valve conditioning system

Figure 5: Cell orientation conditioning bioreactor
Figure 6: Pericardium conditioning bioreactor

Figure 7: Chamber for burst-strength testing
Figure 8: Pulse generator for a vascular graft bioreactor

Project Leader

 

M.Sc., Cand. PhD

Luis Hurtado Aguilar

Tel.: +49 (0) 241 80 89416

hurtado(at)hia.rwth-aachen.de