StartseiteAbteilungenKardiovaskuläre TechnikHerzunterstützung & HerzersatzPublikationen

Publikationen der Gruppe Herzunterstützung & Herzersatz

Bücher

Finocchiaro, T. Untersuchung eines Linearantriebkonzeptes für ein vollständig implantierbares Kunstherz. Aachener Schriftenreihe zur Elektromagnetischen Energiewandlung Band 12. Shaker Verlag 2013

Journal Beiträge

2015

Gräf F, Finocchiaro T, Laumen M, Mager I, Steinseifer U. Mock Circulation Loop to Investigate Hemolysis in a Pulsatile Total Artificial Heart. Artif Organs. 13. Januar 2015; [Epub ahead of print]

Wong KC, Büsen M, Benzinger C, Gäng R, Bezema M, Greatrex N, u. a. Effect of rotary blood pump pulsatility on potential parameters of blood compatibility and thrombosis in inflow cannula tips. Int J Artif Organs. 14. Januar 2015;37(12):875–87. [Epub ahead of print]

2014

Boehning F, Mejia T, Schmitz-Rode T, Steinseifer U. Hemolysis in a laminar flow-through couette shearing device: an experimental study. Artif Organs. September 2014;38(9):761–5.

Cuenca-Navalon E, Finocchiaro T, Laumen M, Fritschi A, Schmitz-Rode T, Steinseifer U. Design and evaluation of a hybrid mock circulatory loop for total artificial heart testing. Int J Artif Organs. Januar 2014;37(1):71–80.

Hsu P-L, Graefe R, Boehning F, Wu C, Parker J, Autschbach R, u. a. Hydraulic and hemodynamic performance of a minimally invasive intra-arterial right ventricular assist device. Int J Artif Organs. 2. Oktober 2014;37(9):697–705.

Hsu P-L, Wang Y, Amaral F, Parker J, Schmitz-Rode T, Autschbach R, u. a. Design method of a foldable ventricular assist device for minimally invasive implantation. Artif Organs. April 2014;38(4):298–308.

Hsu P-L, Hatam N, Unterkofler J, Goetzenich A, McIntyre M, Wong KC, u. a. Selective reduction of afterload in right heart assist therapy: a mock loop study†. Interact Cardiovasc Thorac Surg. Juli 2014;19(1):76–81.

Jansen-Park S-H, Spiliopoulos S, Deng H, Greatrex N, Steinseifer U, Guersoy D, u. a. A monitoring and physiological control system for determining aortic valve closing with a ventricular assist device. Eur J Cardiothorac Surg. September 2014;46(3):356–60.

Koerfer R, Spiliopoulos S, Finocchiaro T, Guersoy D, Tenderich G, Steinseifer U. Paving the way for destination therapy of end-stage biventricular heart failure: the ReinHeart total artificial heart concept. Eur J Cardiothorac Surg. Dezember 2014;46(6):935–6.

Pelletier B, Spiliopoulos S, Finocchiaro T, Graef F, Kuipers K, Laumen M, u. a. System overview of the fully implantable destination therapy-ReinHeart-total artificial heart. Eur J Cardiothorac Surg. Januar 2015;47(1):80–6.

Wong KC, Büsen M, Benzinger C, Gäng R, Bezema M, Greatrex N, u. a. Effect of inflow cannula tip design on potential parameters of blood compatibility and thrombosis. Artif Organs. September 2014;38(9):810–7.

Laumen M., Steinseifer U., Von der Herzunterstützung bis zum vollständigen Herzersatz - Entwicklung von Blutpumpen. Medical Science and Technology, RWTH Themen, 1:6–8, 2014

Egger C, Das erworbene von-Willebrand-Syndrom bei ECLS-Patienten: Wie teste ich Blutpumpen und Oxygenatoren in vitro? Kardiotechnik, 2014; 3-7.

 

Hsu PL, Hatam N, Unterkofler J, Goetzenich A, McIntyre M, Wong KC, Egger C, Schmitz-Rode T, Autschbach R, Steinseifer U: Selective reduction of afterload in right heart assist therapy: a mock loop study. Interact Cardiovasc Thorac Surg. 2014 Jul;19(1):76-81.

2013

Amaral F, Egger C, Steinseifer U, Schmitz-Rode T. Differences between blood and a Newtonian fluid on the performance of a hydrodynamic bearing for rotary blood pumps. Artif Organs. September 2013;37(9):786–92.

Amaral F, Gross-Hardt S, Timms D, Egger C, Steinseifer U, Schmitz-Rode T. The spiral groove bearing as a mechanism for enhancing the secondary flow in a centrifugal rotary blood pump. Artif Organs. Oktober 2013;37(10):866–74.

Boehning F, Timms D, Hsu P-L, Schmitz-Rode T, Steinseifer U. Experimental and Analytical Performance Evaluation of Short Circular Hydrodynamic Journal Bearings Used in Rotary Blood Pumps. Artificial Organs. 2013;37(10):913–20.

Egger C, Maas J, Hufen T, Schmitz-Rode T, Steinseifer U. Establishing a method for in vitro investigation of mechanical parameters causing acquired von Willebrand syndrome in ventricular assist devices. Artif Organs. September 2013;37(9):833–9.

Fritschi AJ, Laumen M, Spiliopoulos S, Finocchiaro T, Egger C, Schmitz-Rode T, u. a. Image based evaluation of mediastinal constraints for the development of a pulsatile total artificial heart. Biomed Eng Online. 2013;12:81.

Hsu P-L, Wang Y, Amaral F, Parker J, Schmitz-Rode T, Autschbach R, u. a. Design Method of a Foldable Ventricular Assist Device for Minimally Invasive Implantation. Artif Organs. 22. August 2013;

Laumen M, Finocchiaro T, Cuenca E, Guersoy D, Spiliopoulos S, Tenderich G, u. a. A Novel Total Artificial Heart for Destination Therapy: In-Vitro and In-Vivo Study. Biomed Tech (Berl). 7. September 2013;

Laumen M. and Pelletier B., Lebensretter Kunstherz – Vollimplantierbares System "ReinHeart". Deutsches Ärzteblatt Praxis, 4(28):11–15, November 2013.

2012

Hsu P-L, Parker J, Egger C, Autschbach R, Schmitz-Rode T, Steinseifer U. Mechanical circulatory support for right heart failure: current technology and future outlook. Artif Organs. April 2012;36(4):332–47.

Po-Lin Hsu, Madeleine McIntyre, Maximilian Kuetting, Jack Parker, Christina Egger, Rudiger Autschbach, u. a. Review of recent patents on foldable ventricular assist devices. Recent Patents on Biomedical Engineering. Dezember 2012;5(3):208–22.

2011

Boehning F, Timms DL, Amaral F, Oliveira L, Graefe R, Hsu PL, Schmitz-Rode T, Steinseifer U. Evaluation of Hydraulic Radial Forces on the Impeller by the Volute in a Centrifugal Rotary Blood Pump. Artif Organs. 2011, 35, 818-825.

A Pohlmann, M Leßmann, T Finocchiaro, A Fritschi, U. Steinseifer, T Schmitz-Rode and K. Hameyer; Drive optimisation of a pulsatile Total Artificial Heart, Archives of Electrical Engineering, volume 60, number 2, pages 169-178, ISSN 0004-0746, 2011,

Andre Pohlmann, Marc Leßmann, Andreas Fritschi, Thomas Finocchiaro, Ulrich Steinseifer and Kay Hameyer; Experimental Validation of the linear drive train for a Total Artificial Heart System; LDIA 2011; Eindhoven; The Netherlands; TU Eindhoven; 112 – 113; ISBN 978-90-386-2523-2; 07; 2011

2010

Borchardt R, Schlanstein P, Arens J, Graefe R, Schreiber F, Schmitz-Rode T, Steinseifer U. Description of a flow optimized oxygenator with integrated pulsatile pump. Artif Organs. 2010, 34, 904-910.

Graefe R, Borchardt R, Arens J, Schlanstein P, Schmitz-Rode T, Steinseifer U. Improving oxygenator performance using computational simulation and flow field based parameters. Artif Organs. 2010, 34, 930-936.

Graefe R, Timms D, Boehning F, Schmitz-Rode T, Steinseifer U. Investigation of the Influence of Volute Design on Journal Bearing Bias Force using CFD. Artif Organs. 2010, 34, 760-765.

Laumen M, Kaufmann T, Timms D, Schlanstein P, Jansen S, Gregory S, Wong KC, Schmitz-Rode T, Steinseifer U.; Flow analysis of ventricular assist device inflow and outflow cannula positioning using a naturally shaped ventricle and aortic branch; Artif Organs. 2010 Oct;34(10):798-806.

2009

T. Finocchiaro, S. Heinke, M. Behbahani, M. Lessmann, M. Laumen, U. Steinseifer, T. Schmitz-Rode, S. Leonhardt, M. Behr, and K. Hameyer; Methods of design, simulation, and control for the development of new vad/tah concepts; Biomed Tech (Berl), 54(5):269–281, 2009.

Kaufmann TA, Hormes M, Laumen M, Timms DL, Schmitz-Rode T, Moritz A, Dzemali O, Steinseifer U; Flow distribution during cardiopulmonary bypass in dependency on the outflow cannula positioning. Artif Organs. 2009;33(11): 988-92

Kaufmann TA, Hormes M, Laumen M, Timms DL, Linde T, Schmitz-Rode T, Moritz A, Dzemali O, Steinseifer U; The impact of aortic/subclavian outflow cannulation for cardiopulmonary bypass and cardiac support: a computational fluid dynamics study. Artif Organs. 2009;33(9): 727-32

Timms D, Schulte-Eistrup S, Boening F, Kraemer M, Frischi A, Graefe R, Kaufmann T, Schmitz-Rode T, Steinseifer U, Koerfer R. Improved Suspension and Physiological Characteristics of the BOCAD LVAD. Int J Artif Organs. 2009;32(7): 424-424.

2008

M. Leßmann, T. Finocchiaro, U. Steinseifer, T. Schmitz-Rode and K. Hameyer, Concepts and designs of life support systems, IET Science, Measurement & Technology, 2(6): 499-505, 2008

Finocchiaro, T.; Butschen, T.; Kwant, P.; Steinseifer, U.; Schmitz-Rode, T.; Hameyer, K. & Lessmann, M; New Linear Motor Concepts for Artificial Hearts; IEEE Trans. Magn., 2008, 44, 678-681

2007

Kwant, P. B.; Finocchiaro T.; Förster, F.; Reul, H.; Rau, G.; Morshuis, M.; Banayosi, A. E.; Körfer, R.; Schmitz-Rode, T. & Steinseifer, U; The MiniACcor: constructive redesign of an implantable total artificial heart, initial laboratory testing and further steps;Int J Artif Organs, Helmholtz Institute, Aachen, Germany, 2007, 30, 345-351

Auszeichnungen

2014

Andreas Fritschi, Mimics Innovation Award, First Prize & Global Award 2014, http://biomedical.materialise.com/mimics-innovation-awards-winners-2014

2012

Projekt ReinHeart, Germany at its best, Das weltweit kleinste Kunstherz, Kategorie Wissenschaft, Region Aachen, germanyatitsbest.de/de/best_performances/categories/

Vorträge

2015

Wappenschmidt J., Götzenich A., Steinseifer U., Autschbach R., A new Approach for an Intracorporal Blood Pump based on the Rotary Piston Engine Principle. 44. Jahrestagung der Deutschen Gesellschaft für Thorax-, Herz- und Gefäßchirurgie (DGTHG), 08-11 Februar in Freiburg, Germany

Egger C., The Impact of Ventricular Assist Device Implantation on the Acquired von Willebrand Syndrome – Comparison of Centrifugal and Axial Design 44. Jahrestagung der Deutschen Gesellschaft für Thorax-, Herz- und Gefäßchirurgie (DGTHG), 08-11 Februar in Freiburg, Germany

2014

Lierath C., Gräf F., Schmitz S., Finocchiaro T., Steinseifer U., Behm H., Dahlmann R., Hopmann Ch., Reducing Water Transmission Rate of Dynamically Loaded Polyurethane Membranes in Pulsatile Blood Pumps. 22nd Congress of the International Society for Rotary Blood Pumps (ISRBP), 25-27 September, San Francisco

Pelletier B., Cuenca E., Carstens P., Finocchiaro T., Steinseifer U., Development of a Data Acquisition and Analysis System for Chronic Animal Trials with Blood Pumps. 22nd Congress of the International Society for Rotary Blood Pumps (ISRBP), 25-27 September, San Francisco

Wappenschmidt J., Götzenich A., Steinseifer U., Autschbach R., Seal-less Drive and Bearing: A Viable Approach for a Blood Pump based on the Rotary Piston Engine Principle. 22nd Congress of the International Society for Rotary Blood Pumps (ISRBP), 25-27 September, San Francisco

Egger C., Acquired von Willebrand Syndrome in VAD Patients: How fast does it occur? 22nd Congress of the International Society for Rotary Blood Pumps (ISRBP), 25-27 September, San Francisco

Groß-Hardt S.,Ali A.,Steinseifer U.,Transient numerical assessment of the risk of thrombus formation in an implantable centrifugal blood pump. 41st ESAO, 17-20 September, Rome

Groß-Hardt S.,Steinseifer U.,Simulation driven development of medical devices using response surface based optimisation. 41st ESAO, 17-20 September, Rome

S.Schmitz, P.Henning, J.Maas, I.Mager, U.Steinseifer  High influence of prostheses surface properties on thrombogenicity 41st ESAO, 17-20 September, Rome

2013

Groß-Hardt S.,Graefe R.,Steinseifer U.,Numerical Method for Pump Geometry Optimization using Computational Fluid Dynamics and Goal Driven Optimization. 21st Congress of the International Society for Rotary Blood Pumps (ISRBP 2013) in September 26-28, 2013 in Yokohama, Japan

Wappenschmidt J., Roggenkamp J., Egger C., Unterkofler J., Steinseifer U., Autschbach R., Concept Study of a Total Artificial Heart based on the Rotary Piston Engine Principle. 21st Congress of the International Society for Rotary Blood Pumps (ISRBP 2013) in September 26-28, 2013 in Yokohama, Japan

Groß-Hardt S.,Graefe R.,Steinseifer U.,Numerical Investigation of the interaction of rotary ventricular assist devices with the human circulatory system and the organ perfusion. 1.MPF2013 - V International Symposium on Modelling of Physiological Flows, Chia Laguna, June 11-14, 2013 2.Assisted Circulation (GRS), Gordon Research Seminar, June 22-23, 2013,Renaissance Tuscany Il Ciocco Resort, Lucca (Barga), Italy

Laumen M., T. Finocchiaro, E. Cuenca, D. Guersoy, S. Spiliopoulos, G. Tenderich, T. Schmitz-Rode, R. Körfer, and U. Steinseifer. A novel fully implantable total artificial heart: In vitro and in vivo study. In 40th ESAO Congress, Glasgow, Scotland, UK, September 2013.

Laumen M., T. Finocchiaro, E. Cuenca, D. Guersoy, S. Spiliopoulos, G. Tenderich, T. Schmitz-Rode, R. Körfer, and U. Steinseifer. A novel total artificial heart for destination therapy: In-vitro and in-vivo study. In BMT, Graz, Austria, 2013.

 

Finocchiaro, T; Gräf, F; Nadzeyka, I; Steinseifer, U  Development of adaptable protheses to connect a total artificial heart 40th ESAO Congress, Glasgow, Scotland, UK, September 2013

2012

Laumen M., E. Cuenca, T. Finocchiaro, K. Kuipers, C. Egger, F. Jung, T Schmitz-Rode, and U. Steinseifer. Left right flow balance investigation of a total artificial heart. In ESAO, 39th Annual Conference, Rostock, Germany, 2012.

 2011

coming

2010

Finocchiaro T., Cuenca Navalon E., Fiehe S., Fritschi A., Heinke S., Spillner J., Autschbach R., Leonhardt S., Laumen M.,Timms D., Schmitz-Rode T., Steinseifer U.; Software Controlled Mock Circulation Loop for Validation of TAH and VAD Controls; ESAO Congress, Skopje; 2010.

Finocchiaro T. et al; ReinHeart Device Update, 5th European Mechanical Circulatory Support Summit, Bad Oeynhausen, 2010.

2009

Laumen, M., Kaufmann T., Timms D., Gregory, S., Moritz, A., Schmitz-Rode T., Steinseifer U.; Flow Analysis of VAD in- and outflow cannula positioning using a naturally shaped ventricle and aortic branch, Congress of the International Society for Rotary Blood Pumps (ISRBP), 1-3 October 2009, Singapore

Fritschi, A; Kwant, PB; Finocchiaro, T; Cuenca-Navalon, E; Laumen, L; Schmitz-Rode, T; Steinseifer, U; Conceptual design of a centrifugal integrated pump for heart recovery; The International Society for Rotary Blood Pumps Annual Meeting, Singapore, 2009

Finocchiaro T, Fritschi A, Navalon EC, Schmitz-Rode T, Morshuis M, Korfer R, Schulte-Eistrup S, Steinseifer U; Analysis of flow patterns in the Total Artificial Heart “ReinHeart”, ESAO Conference 2009, Int J Artif Organs. 2009;32(7): 392-392

Finocchiaro T., Safi S., Gester K., Steinseifer U., Schmitz-Rode T.;Sonderanwendungen von dynamischen und statischen zugversuchen in der kardiovaskulären Technik, Medizin Symposium, Ulm, Fa. Zwick, 2009.

M. Laumen, T. Finocchiaro, A. Fritschi, E. Cuenca Navalon, T. Schmitz-Rode, M. Morshuis, R. Körfer, S. Schulte-Eistrup, U. Steinseifer; ANALYSIS OF FLOW PATTERNS IN THE TOTAL ARTIFICIAL HEART “REINHEART”; Esaio 2009, Compiègne, France; Int J Artif Organs. 2009;32(7): 392-392

Penzkofer T, Bruners P, Isfort P, Elfring R, Fritschi A, Van Roost F, Hormes M, Günther R, Schmitz-Rode T, Mahnken AH;
Vascular Electromagnetic Tracking: experiences in phantom and animal cadaveric models; World Congress 2009 München

2008

Finocchiaro T., Laumen M., Cuenca E., Fritschi A., Steinseifer U., Schmitz-Rode T., Schulte-Eistrup S., Morshuis M. & Körfer R.; ACcor - Total Artificial Heart, 3rd European Mechanical Circulatory Support Summit, 2008.

S. Schulte-Eistrup, A. Fritschi, D. Timms, T. Finocchiaro, M. Morshuis, U. Steinseifer, T. Schmitz-Rode, R. Körfer; BOCAD - Bad Oeynhausen Cardiac Assist Device, 3rd European Mechanical Circulatory Support Summit, 2008.

Laumen M, Finocchiaro T, Schmitz-Rode T, Korfer R, Banayosy AE, Steinseifer U; GEOMETRY AND FLOW OPTIMIZATION OF THE AACHEN TOTAL ARTIFICIAL HEART  "ACcor"; ESAO Conference 2008, Int J Artif Organs. 2008;31(7): 594-594

Laumen M., Finocchiaro T., Gräf F. Schmitz-Rode T., Schulte-Eistrup S., Körfer R., Steinseifer U.;  Optimization of the Aachen total artificial heart “ACcor” - Anatomic fitting and flow measurement; eMBEC Congress 2008, Engineering for Health, 23-27 November 2008, Antwerp, Belgium17th

Laumen M. Strömungsmessung an künstlichen Organen. In Dantec Dynamics User Meeting, Hamburg, Germany, 2008.

2007

Finocchiaro T., Kwant P. B., Banajosi A. E., Koerfer R., Schmitz-Rode T. & Steinseifer U.; ACcor, Aachen Total Artificial Heart, 41. Jahrestagung der Deutschen Gesellschaft für Biomedizinische Technik, Aachen, 2007.

2006

Finocchiaro T., Kwant P. B., Kaufmann R., Verkroost M., Stienseifer U. & Schmitz-Rode T.; VERSUS Ventricular Recovery Support System, Gemeinsame Jahrestagung derDeutschen, Schweizerischen und Österreichischen Gesellschaft für biomedizinische Technik, Zürich, 2006.

Finocchiaro T., Kwant P. B., Steinseifer U., Verkroost M., Brouwer R., Rakhorst G. & Schmitz-Rode T.; VERSUS (VEntricular Recovery SUpport System) status update , World Congress of Biomechanics, München, 2006.

2004

Finocchiaro T., Mussmann B., Kwant P. B. & Reul H.;Regelung eines pulsatilen Herzunterstützungssystems (VAD); Tagungsband Automed; 2004.

Poster

2015

Wappenschmidt J., Götzenich A., Steinseifer U., Autschbach R., A new Approach for an Intracorporal Blood Pump based on the Rotary Piston Engine Principle. 44. Jahrestagung der Deutschen Gesellschaft für Thorax-, Herz- und Gefäßchirurgie (DGTHG), 08-11 Februar in Freiburg, Germany

2014

B. Pelletier, Y. Blaszczyk, T. Schmitz-Rode, U. Steinseifer; Position Sensing Development For Pulsatile Blood Pumps; ASAIO 60th Annual Conference, June 18-21, 2014, Washington DC

 

S. Schmitz; M. Sedlaczek; K. Kuipers; F. Graef; S. Spiliopoulos; R. Koerfer; U. Steinseifer; Development of an Implantable Compliance Chamber for a Total Artificial Heart; ASAIO 60th Annual Conference, June 18-21, 2014, Washington DC

2013

Gross-Hardt S, Amaral F, Roland Graefe, Steinseifer U, Schmitz-Rode T. Volute Design Considerations for Stable Impeller Suspension In Hydrodynamically Suspended Rotary Blood Pumps Using Computational Fluid Dynamics. Assisted Circulation (GRS), Gordon Research Seminar, June 22-23, 2013,Renaissance Tuscany Il Ciocco Resort, Lucca (Barga), Italy

2012

Gräf, F., M. Laumen, I. Mager, C. Egger, T. Schmitz-Rode, and U. Steinseifer. In Vitro Blood Damage Testing of a Pulsatile Artificial Heart with a Newly Designed Mock Loop, 2012

Laumen M., E. Cuenca, T. Finocchiaro, K. Kuipers, C. Egger, T. Schmitz-Rode, and U. Steinseifer. Investigation of left right flow balancing approaches of the reinheart total artificial heart, 2012.

Sonntag J. S., T. Kaufmann, M. Laumen, T. Linde, T Schmitz-Rode, and Steinseifer U. Fully coupled 3d fluid structure interaction simulations of a total artificial heart, 2012

2011

A. J. Fritschi, M. Laumen, T. Finocchiaro, M. Halai, S. Spiliopoulos, S. Schulte-Eistrup, C. Egger, T. Schmitz-Rode, U. Steinseifer; Computer Aided Anatomical Fitting as a method to improve the design of Cardiovascular Implants; ESAO and IFAO Congress Porto, Int J Artif Organs, 34(8):706–707,

2010

coming

2009

D. Timms, S. Schulte-Eistrup, F. Boening, M. Kraemer, A. Frischi, R. Graefe, T. Kaufmann, T. Schmitz-Rode, U. Steinseifer, R Koerfer;
Improved suspension and physiological characteristics of the bocad LVAD; Int J Artif Organs. 2009;32(7): 424-424

D. Timms, S. Schulte‐Eistrup, F. Boehning, A. Fritschi, T. Kaufmann, T. Schmitz‐Rode, U. Steinseifer, R. Koerfer; The BoCad LVAD – An inexpensive device for cardiac assistance, ASAO 2009, Dallas:

2008

M. Leßmann, T. Finocchiaro, U. Steinseifer, T. Schmitz-Rode and K. Hameyer, Concepts and designs of life support systems, The 7th International Conference on Computation in Electromagnetics, CEM, Brighton, UK, April 2008

T. Finocchiaro, R. Körfer, M. Leßmann, K. Hameyer, T. Schmitz-Rode and U. Steinseifer, New Drive Concepts for the Aachen Total Artificial Heart, The 55th Anual Conference, ASAIO, San Francisco, USA June 2008

T. Finocchiaro, U. Steinseifer, T. Schmitz-Rode, K. Hameyer, M. Leßmann, R. Körfer and M. Laumen, Direct drive concepts fort he Aachen Total Artificial Heart
, The European Society of Artificial Organs Annual Meeting, Cetre Médical Universitaire, Genevo, Switzerland, September 2008

Patente

coming